Phagocytosis and Immunity

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Inborn Errors of Immunity and Phagocytosis

(active) and Ab-mediated (passive) enhancement. The opsonization of antigen recognition cells versus production of anti-idiotypic antibody theories of passive enhancement are then presented and evaluated. Subsequent chapters, excellent in depth and coverage, deal with: (i) the role and possible mechanisms of action of antiidiotypic antisera on Band T-lymphocytes; (ii) the use of donor-specific ...

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Phagocytosis, Innate Immunity, and Host–Pathogen Specificity

In mammals, phagocytosis is essential for a variety of biological events, including tissue remodeling and the continuous clearance of dying cells. Furthermore, phagocytosis represents an early and crucial event in triggering host defenses against invading pathogens, which is the focus of this commentary. Phagocytosis comprises a series of events, starting with the binding and recognition of par...

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Phagocytosis: A Fundamental Process in Immunity

One hundred years have passed since the death of Élie Metchnikoff (1845-1916). He was the first to observe the uptake of particles by cells and realized the importance of this process for the host response to injury and infection. He also was a strong advocate of the role of phagocytosis in cellular immunity, and with this he gave us the basis for our modern understanding of inflammation and th...

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Phagocytosis: at the crossroads of innate and adaptive immunity.

Phagocytosis, the process by which cells engulf large particles, requires a substantial contribution of membranes. Recent studies have revealed that intracellular compartments, including endocytic organelles and the endoplasmic reticulum (ER), can engage in fusion events with the plasma membrane at the sites of nascent phagosomes. The finding that ER proteins are delivered to phagosomes, where ...

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Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role in innate immunity by eliminating pathogenic bacteria, fungi and malignant cells, and contribute to adaptive immunity by presenting antigens to lymphocytes. In addition, phagocytes play a part in ...

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ژورنال

عنوان ژورنال: Journal of Comparative Pathology and Therapeutics

سال: 1892

ISSN: 0368-1742

DOI: 10.1016/s0368-1742(92)80003-6